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Associate Professor Deborah Cromer

Associate Professor Deborah Cromer

Associate Professor

PhD in Mathematical Biology (Imperial College, London UK, 2008)
BSc (Hons Class 1 and University Medal) in Mathematics and Computer Science (¹úÃñ²ÊƱ, 2000)
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Medicine & Health
The Kirby Institute

Associate Professor Deborah Cromer leads the ÌýinÌýtheÌýÌýat the , ¹úÃñ²ÊƱ. She has made significant contributions to understanding immune correlates of infection for COVID-19, and her work has influenced vaccination policy internationally. She is a member of the . She has also assisted with public understanding of immunity and vaccination through frequent media contributions and appearances, and presentations in public science forums and to school students. She is passionate about encouraging and supporting females to engage and excel in mathematics. She holds an NHMRC Investigator Fellowship.

Specific Research Keywords:
COVID-19, SARS-CoV-2, Mathematical Biology, Mathematical Modelling, Mathematics, Malaria, Theoretical Biology, HIV, CMV, Vaccination Policy, Influenza, Rotavirus, RSV
Phone
9385 8194
E-mail
d.cromer@unsw.edu.au
  • Journal articles | 2025
    Claiborne DT; Detwiler Z; Docken SS; Borland TD; Cromer D; Simkhovich A; Ophinni Y; Okawa K; Bateson T; Chen T; Hudson W; Trifonova R; Davenport MP; Ho TW; Boutwell CL; Allen TM, 2025, 'High frequency CCR5 editing in human hematopoietic stem progenitor cells protects xenograft mice from HIV infection', Nature Communications, 16,
    Journal articles | 2025
    Hao T; Ryan GE; Lydeamore MJ; Cromer D; Wood JG; McVernon J; McCaw JM; Shearer FM; Golding N, 2025, 'Predicting immune protection against outcomes of infectious disease from population-level effectiveness data with application to COVID-19', Vaccine, 55,
    Journal articles | 2025
    Lee WS; Selva KJ; Audsley J; Kent HE; Reynaldi A; Schlub TE; Cromer D; Khoury DS; Peck H; Aban M; Vu MN; Zheng MZM; Chung AW; Koutsakos M; Tan HX; Wheatley AK; Juno JA; Rockman S; Davenport MP; Barr I; Kent SJ, 2025, 'Randomized trial of same- versus opposite-arm coadministration of inactivated influenza and SARS-CoV-2 mRNA vaccines', JCI Insight, 10,
    Journal articles | 2024
    Cromer D; Reynaldi A; Mitchell A; Schlub TE; Juno JA; Wheatley AK; Kent SJ; Khoury DS; Davenport MP, 2024, 'Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates', Nature Communications, 15,
    Journal articles | 2024
    Elias KM; Khan SR; Stadler E; Schlub TE; Cromer D; Polizzotto MN; Kent SJ; Turner T; Davenport MP; Khoury DS, 2024, 'Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: a systematic review and meta-analysis', The Lancet Microbe, 5, pp. e459 - e467,
    Journal articles | 2024
    Hastak P; Cromer D; Malycha J; Andersen CR; Raith E; Davenport MP; Plummer M; Sasson SC, 2024, 'Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia', Scientific Reports, 14,
    Journal articles | 2024
    Revoltar M; van der Linde R; Cromer D; Gatt PN; Smith S; Fernandez MA; Vaughan L; Blyth E; Curnow J; Tegg E; Brown DA; Sasson SC, 2024, 'Indeterminate measurable residual disease by multiparameter flow cytometry is associated with an intermediate risk of clinical relapse in adult patients with acute leukaemia', Pathology, 56, pp. 882 - 888,
    Journal articles | 2023
    Cromer D; Steain M; Reynaldi A; Schlub TE; Khan SR; Sasson SC; Kent SJ; Khoury DS; Davenport MP, 2023, 'Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis', Nature Communications, 14, pp. 1633,
    Journal articles | 2023
    Docken SS; McCormick K; Pampena MB; Samer S; Lindemuth E; Pinkevych M; Viox EG; Wu Y; Schlub TE; Cromer D; Keele BF; Paiardini M; Betts MR; Bar KJ; Davenport MP, 2023, 'Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency', PLoS Pathogens, 19,
    Journal articles | 2023
    Khoury DS; Docken SS; Subbarao K; Kent SJ; Davenport MP; Cromer D, 2023, 'Predicting the efficacy of variant-modified COVID-19 vaccine boosters', Nature Medicine, 29, pp. 574 - 578,
    Journal articles | 2023
    Khoury DS; Schlub TE; Cromer D; Steain M; Fong Y; Gilbert PB; Subbarao K; Triccas JA; Kent SJ; Davenport MP, 2023, 'Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection', Emerging Infectious Diseases, 29, pp. 381 - 388,
    Journal articles | 2023
    Lee WS; Tan HX; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent HE; Aggarwal A; Turville SG; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson DA; Cromer D; Davenport MP; Kent SJ; Juno JA; Khoury DS; Wheatley AK, 2023, 'Durable reprogramming of neutralizing antibody responses following Omicron breakthrough infection', Science Advances, 9,
    Journal articles | 2023
    Selva KJ; Ramanathan P; Haycroft ER; Reynaldi A; Cromer D; Tan CW; Wang LF; Wines BD; Hogarth PM; Downie LE; Davis SK; Purcell RA; Kent HE; Juno JA; Wheatley AK; Davenport MP; Kent SJ; Chung AW, 2023, 'Preexisting immunity restricts mucosal antibody recognition of SARS-CoV-2 and Fc profiles during breakthrough infections', JCI Insight, 8,
    Journal articles | 2023
    Stadler E; Burgess MT; Schlub TE; Khan SR; Chai KL; McQuilten ZK; Wood EM; Polizzotto MN; Kent SJ; Cromer D; Davenport MP; Khoury DS, 2023, 'Monoclonal antibody levels and protection from COVID-19', Nature Communications, 14, pp. 4545,
    Journal articles | 2023
    Stadler E; Chai KL; Schlub TE; Cromer D; Khan SR; Polizzotto MN; Kent SJ; Beecher C; White H; Turner T; Skoetz N; Estcourt L; McQuilten ZK; Wood EM; Khoury DS; Davenport MP, 2023, 'Determinants of passive antibody efficacy in SARS-CoV-2 infection: a systematic review and meta-analysis', The Lancet Microbe, 4, pp. e883 - e892,
    Journal articles | 2023
    Stadler E; Cromer D; Ogunlade S; Ongoiba A; Doumbo S; Kayentao K; Traore B; Crompton PD; Portugal S; Davenport MP; Khoury DS, 2023, 'Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data', Malaria Journal, 22,
    Journal articles | 2023
    Zachreson C; Tobin R; Szanyi J; Walker C; Cromer D; Shearer FM; Conway E; Ryan G; Cheng A; McCaw JM; Geard N, 2023, 'Individual variation in vaccine immune response can produce bimodal distributions of protection', Vaccine, 41, pp. 6630 - 6636,
    Journal articles | 2022
    Aggarwal A; Stella A; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Lenthall H; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2022, 'SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern', ,
    Journal articles | 2022
    Aggarwal A; Stella AO; Walker G; Akerman A; Esneau C; Milogiannakis V; Burnett DL; McAllery S; Silva MR; Lu Y; Foster CSP; Brilot F; Pillay A; Van Hal S; Mathivanan V; Fichter C; Kindinger A; Hoppe AC; Munier ML; Amatayakul-Chantler S; Roth N; Coppola G; Symonds GP; Schofield P; Jackson J; Lenthall H; Henry JY; Mazigi O; Jäck HM; Davenport MP; Darley DR; Matthews GV; Khoury DS; Cromer D; Goodnow CC; Christ D; Robosa R; Starck DJ; Bartlett NW; Rawlinson WD; Kelleher AD; Turville SG, 2022, 'Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia', Nature Microbiology, 7, pp. 896 - 908,
    Journal articles | 2022
    Cele S; Jackson L; Khoury DS; Khan K; Moyo-Gwete T; Tegally H; San JE; Cromer D; Scheepers C; Amoako DG; Karim F; Bernstein M; Lustig G; Archary D; Smith M; Ganga Y; Jule Z; Reedoy K; Hwa SH; Giandhari J; Blackburn JM; Gosnell BI; Abdool Karim SS; Hanekom W; Davies MA; Hsiao M; Martin D; Mlisana K; Wibmer CK; Williamson C; York D; Harrichandparsad R; Herbst K; Jeena P; Khoza T; Kløverpris H; Leslie A; Madansein R; Magula N; Manickchund N; Marakalala M; Mazibuko M; Moshabela M; Mthabela N; Naidoo K; Ndhlovu Z; Ndung’u T; Ngcobo N; Nyamande K; Patel V; Smit T; Steyn A; Wong E; von Gottberg A; Bhiman JN; Lessells RJ; Moosa MYS; Davenport MP; de Oliveira T; Moore PL; Sigal A, 2022, 'Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization', Nature, 602, pp. 654 - 656,
    Journal articles | 2022
    Cromer D; Reynaldi A; Steain M; Triccas JA; Davenport MP; Khoury DS, 2022, 'Relating in Vitro Neutralization Level and Protection in the CVnCoV (CUREVAC) Trial', Clinical Infectious Diseases, 75, pp. E878 - E879,
    Journal articles | 2022
    Cromer D; Steain M; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Kent SJ; Triccas JA; Khoury DS; Davenport MP, 2022, 'Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis', The Lancet Microbe, 3, pp. e52 - e61,
    Journal articles | 2022
    Kent SJ; Khoury DS; Reynaldi A; Juno JA; Wheatley AK; Stadler E; John Wherry E; Triccas J; Sasson SC; Cromer D; Davenport MP, 2022, 'Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?', Nature Reviews Immunology, 22, pp. 387 - 397,
    Journal articles | 2022
    Koutsakos M; Lee WS; Reynaldi A; Tan HX; Gare G; Kinsella P; Liew KC; Taiaroa G; Williamson DA; Kent HE; Stadler E; Cromer D; Khoury DS; Wheatley AK; Juno JA; Davenport MP; Kent SJ, 2022, 'The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants', Immunity, 55, pp. 1316 - 1326.e4,
    Journal articles | 2022
    SheelaNair A; Romanczuk AS; Aogo RA; Haldar RN; Lansink LIM; Cromer D; Salinas YG; Guy RK; McCarthy JS; Davenport MP; Haque A; Khoury DS, 2022, 'Similarly efficacious anti-malarial drugs SJ733 and pyronaridine differ in their ability to remove circulating parasites in mice', Malaria Journal, 21,
    Journal articles | 2022
    Stadler E; Cromer D; Mehra S; Adekunle AI; Flegg JA; Anstey NM; Watson JA; Chu CS; Mueller I; Robinson LJ; Schlub TE; Davenport MP; Khoury DS, 2022, 'Population heterogeneity in Plasmodium vivax relapse risk', PLoS Neglected Tropical Diseases, 16,
    Journal articles | 2022
    2022, 'PP 2.3 – 00034 CD8+ T-Cell Sieving During SIV Reactivation from Latency', Journal of Virus Eradication, 8, pp. 100159 - 100159,
    Journal articles | 2021
    Cromer D; Juno JA; Khoury D; Reynaldi A; Wheatley AK; Kent SJ; Davenport MP, 2021, 'Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection', Nature Reviews Immunology, 21, pp. 395 - 404,
    Journal articles | 2021
    Cromer D; Reynaldi A; Steain M; Triccas J; Davenport M; Khoury D, 2021, 'Relating in vitro neutralisation level and protection in the CVnCoV (CUREVAC) trial', ,
    Journal articles | 2021
    Cromer D; Steain M; Reynaldi A; Schlub T; Wheatley A; Juno J; Kent S; Triccas J; Khoury D; Davenport M, 2021, 'SARS-CoV-2 variants: levels of neutralisation required for protective immunity', ,
    Journal articles | 2021
    Khoury D; Cromer D; Reynaldi A; Schlub T; Wheatley A; Juno J; Subbarao K; Kent S; Triccas J; Davenport M, 2021, 'What level of neutralising antibody protects from COVID-19?', ,
    Journal articles | 2021
    Khoury DS; Cromer D; Reynaldi A; Schlub TE; Wheatley AK; Juno JA; Subbarao K; Kent SJ; Triccas JA; Davenport MP, 2021, 'Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection', Nature Medicine, 27, pp. 1205 - 1211,
    Journal articles | 2021
    Lee WS; Selva KJ; Davis SK; Wines BD; Reynaldi A; Esterbauer R; Kelly HG; Haycroft ER; Tan HX; Juno JA; Wheatley AK; Hogarth PM; Cromer D; Davenport MP; Chung AW; Kent SJ, 2021, 'Decay of Fc-dependent antibody functions after mild to moderate COVID-19', Cell Reports Medicine, 2,
    Journal articles | 2021
    Pymm P; Adair A; Chan LJ; Cooney JP; Mordant FL; Allison CC; Lopez E; Haycroft ER; O'Neill MT; Tan LL; Dietrich MH; Drew D; Doerflinger M; Dengler MA; Scott NE; Wheatley AK; Gherardin NA; Venugopal H; Cromer D; Davenport MP; Pickering R; Godfrey DI; Purcell DFJ; Kent SJ; Chung AW; Subbarao K; Pellegrini M; Glukhova A; Tham WH, 2021, 'Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice', Proceedings of the National Academy of Sciences of the United States of America, 118,
    Journal articles | 2021
    Wheatley AK; Juno JA; Wang JJ; Selva KJ; Reynaldi A; Tan HX; Lee WS; Wragg KM; Kelly HG; Esterbauer R; Davis SK; Kent HE; Mordant FL; Schlub TE; Gordon DL; Khoury DS; Subbarao K; Cromer D; Gordon TP; Chung AW; Davenport MP; Kent SJ, 2021, 'Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19', Nature Communications, 12,
    Journal articles | 2021
    Wheatley AK; Pymm P; Esterbauer R; Dietrich MH; Lee WS; Drew D; Kelly HG; Chan LJ; Mordant FL; Black KA; Adair A; Tan HX; Juno JA; Wragg KM; Amarasena T; Lopez E; Selva KJ; Haycroft ER; Cooney JP; Venugopal H; Tan LL; O Neill MT; Allison CC; Cromer D; Davenport MP; Bowen RA; Chung AW; Pellegrini M; Liddament MT; Glukhova A; Subbarao K; Kent SJ; Tham WH, 2021, 'Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain', Cell Reports, 37,
    Journal articles | 2020
    Alahmadi A; Belet S; Black A; Cromer D; Flegg JA; House T; Jayasundara P; Keith JM; McCaw JM; Moss R; Ross JV; Shearer FM; Tun STT; Walker CR; White L; Whyte JM; Yan AWC; Zarebski AE, 2020, 'Influencing public health policy with data-informed mathematical models of infectious diseases: Recent developments and new challenges', Epidemics, 32,
    Journal articles | 2020
    Khoury DS; Wheatley AK; Ramuta MD; Reynaldi A; Cromer D; Subbarao K; O’Connor DH; Kent SJ; Davenport MP, 2020, 'Measuring immunity to SARS-CoV-2 infection: comparing assays and animal models', Nature Reviews Immunology, 20, pp. 727 - 738,
    Journal articles | 2020
    Khoury DS; Zaloumis SG; Grigg MJ; Haque A; Davenport MP; Cromer D; Rebelo M; Cao P; McCaw JM; Simpson JA; Flegg JA; Wilson DW; Anstey NM; McCarthy JS, 2020, 'Malaria Parasite Clearance: What Are We Really Measuring?', Trends in Parasitology, 36, pp. 413 - 426,
    Journal articles | 2020
    Price DJ; Shearer FM; Meehan MT; McBryde E; Moss R; Golding N; Conway EJ; Dawson P; Cromer D; Wood J; Abbott S; McVernon J; McCaw JM, 2020, 'Early analysis of the australian covid-19 epidemic', eLife, 9, pp. 1 - 14,
    Journal articles | 2020
    Wu Y; Pinkevych M; Xu Z; Keele BF; Davenport MP; Cromer D, 2020, 'Impact of fluctuation in frequency of human immunodeficiency virus/simian immunodeficiency virus reactivation during antiretroviral therapy interruption', Proceedings of the Royal Society B: Biological Sciences, 287,
    Journal articles | 2019
    Akter J; Khoury DS; Aogo R; Lansink LIM; SheelaNair A; Thomas BS; Laohamonthonkul P; Pernold CPS; Dixon MWA; Soon MSF; Fogg LG; Engel JA; Elliott T; Sebina I; James KR; Cromer D; Davenport MP; Haque A, 2019, 'Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells', PLoS Pathogens, 15, pp. e1007599,
    Journal articles | 2019
    Davenport MP; Khoury DS; Cromer D; Lewin SR; Kelleher AD; Kent SJ, 2019, 'Functional cure of HIV: the scale of the challenge', Nature Reviews Immunology, 19, pp. 45 - 54,
    Journal articles | 2019
    Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2019, 'Corrigendum: Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration (Journal of Infectious Diseases (2016) 214 (753-761) DOI: 10.1093/infdis/jiw234)', Journal of Infectious Diseases, 219, pp. 1852 - 1853,
    Journal articles | 2019
    Pinkevych M; Fennessey CM; Cromer D; Reid C; Trubey CM; Lifson JD; Keele BF; Davenport MP, 2019, 'Predictors of SIV recrudescence following antiretroviral treatment interruption', eLife, 8, pp. e49022,
    Journal articles | 2018
    Aogo RA; Khoury DS; Cromer D; Elliott T; Akter J; Fogg LG; Nair AS; Liligeto UN; Soon MSF; Thomas BS; Pernold CPS; Romanczuk AS; Laohamonthonkul P; Haque A; Davenport MP, 2018, 'Quantification of host-mediated parasite clearance during blood-stage Plasmodium infection and anti-malarial drug treatment in mice', International Journal for Parasitology, 48, pp. 903 - 913,
    Journal articles | 2018
    Khoury DS; Aogo R; Randriafanomezantsoa-Radohery G; McCaw JM; Simpson JA; McCarthy JS; Haque A; Cromer D; Davenport MP, 2018, 'Within-host modeling of blood-stage malaria', Immunological Reviews, 285, pp. 168 - 193,
    Journal articles | 2018
    Parsons MS; Cromer D; Davenport MP; Kent SJ, 2018, 'HIV Reactivation after Partial Protection by Neutralizing Antibodies', Trends in Immunology, 39, pp. 359 - 366,
    Journal articles | 2018
    Pinkevych M; Fennessey CM; Cromer D; Tolstrup M; Søgaard OS; Rasmussen TA; Keele BF; Davenport MP, 2018, 'Estimating initial viral levels during simian immunodeficiency virus/human immunodeficiency virus reactivation from latency', Journal of Virology, 92,
    Journal articles | 2018
    Zaloumis SG; Cao P; Dini S; Davenport MP; Cromer D; Khoury DS; Fowkes FJI; McCaw JM; Simpson JA, 2018, 'In silico investigation of the decline in clinical efficacy of artemisinin combination therapies due to increasing artemisinin and partner drug resistance', Antimicrobial Agents and Chemotherapy, 62, pp. 10.1128/aac.01292 - 10.1128/aac.01218,
    Journal articles | 2017
    Cao P; Klonis N; Zaloumis S; Khoury DS; Cromer D; Davenport MP; Tilley L; Simpson JA; McCaw JM, 2017, 'A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection', Journal of Theoretical Biology, 430, pp. 117 - 127,
    Journal articles | 2017
    Cromer D; Pinkevych M; Rasmussen TA; Lewin SR; Kent SJ; Davenport MP, 2017, 'Modeling of antilatency treatment in HIV: What is the optimal duration of antiretroviral therapy-free HIV remission?', Journal of Virology, 91, pp. 10.1128/jvi.01395 - 10.1128/jvi.01317,
    Journal articles | 2017
    Cromer D; van Hoek AJ; Newall AT; Pollard AJ; Jit M, 2017, 'Burden of paediatric respiratory syncytial virus disease and potential effect of different immunisation strategies: a modelling and cost-effectiveness analysis for England', The Lancet Public Health, 2, pp. e367 - e374,
    Journal articles | 2017
    Khoury DS; Cromer D; Akter J; Sebina I; Elliott T; Thomas BS; Soon MSF; James KR; Best SE; Haque A; Davenport MP, 2017, 'Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection', Proceedings of the National Academy of Sciences of the United States of America, 114, pp. 7701 - 7706,
    Journal articles | 2017
    Khoury DS; Cromer D; Elliott T; Soon MSF; Thomas BS; James KR; Best SE; Aogo RA; Engel JA; Gartlan KH; Akter J; Sebina I; Haque A; Davenport MP, 2017, 'Characterising the effect of antimalarial drugs on the maturation and clearance of murine blood-stage Plasmodium parasites in vivo', International Journal for Parasitology, 47, pp. 913 - 922,
    Journal articles | 2016
    Adekunle AI; Cromer D; Davenport MP, 2016, 'Artemisinin-based treatments in pregnant women with malaria', New England Journal of Medicine, 375, pp. 283,
    Journal articles | 2016
    Cromer D; Grimm AJ; Schlub TE; Mak J; Davenport MP, 2016, 'Estimating the in-vivo HIV template switching and recombination rate', AIDS, 30, pp. 185 - 192,
    Journal articles | 2016
    Cromer D; Schlub TE; Smyth RP; Grimm AJ; Chopra A; Mallal S; Davenport MP; Mak J, 2016, 'HIV-1 mutation and recombination rates are different in macrophages and T-cells', Viruses, 8, pp. 118,
    Journal articles | 2016
    Griffin P; Pasay C; Elliott S; Sekuloski S; Sikulu M; Hugo L; Khoury D; Cromer D; Davenport M; Sattabongkot J; Ivinson K; Ockenhouse C; McCarthy J, 2016, 'Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission', PLoS Neglected Tropical Diseases, 10, pp. e0005139,
    Journal articles | 2016
    Khoury DS; Cromer D; Möhrle JJ; McCarthy JS; Davenport MP, 2016, 'Defining the effectiveness of antimalarial chemotherapy: Investigation of the lag in parasite clearance following drug administration', Journal of Infectious Diseases, 214, pp. 753 - 761,
    Journal articles | 2016
    Pinkevych M; Cromer D; Tolstrup M; Grimm AJ; Cooper DA; Lewin SR; Søgaard OS; Rasmussen TA; Kent SJ; Kelleher AD; Davenport MP, 2016, 'Erratum: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission (PLoS Pathogens (2015) 11:7 (e1005000) DOI: 10.1371/journal.ppat.1005000)', PLoS Pathogens, 12, pp. e1005745,
    Journal articles | 2016
    Pinkevych M; Kent SJ; Tolstrup M; Lewin SR; Cooper DA; Søgaard OS; Rasmussen TA; Kelleher AD; Cromer D; Davenport MP, 2016, 'Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5–8 Days', PLoS Pathogens, 12, pp. e1005740,
    Journal articles | 2015
    Adekunle AI; Pinkevych M; McGready R; Luxemburger C; White LJ; Nosten F; Cromer D; Davenport MP, 2015, 'Modeling the Dynamics of Plasmodium vivax Infection and Hypnozoite Reactivation In Vivo', PLoS Neglected Tropical Diseases, 9, pp. e0003595,
    Journal articles | 2015
    Bilcke J; Chapman R; Atchison C; Cromer D; Johnson H; Willem L; Cox M; Edmunds WJ; Jit M, 2015, 'Quantifying Parameter and Structural Uncertainty of Dynamic Disease Transmission Models Using MCMC: An Application to Rotavirus Vaccination in England and Wales', Medical Decision Making, 35, pp. 633 - 647,
    Journal articles | 2015
    Fraser ST; Midwinter RG; Coupland LA; Kong S; Berger BS; Yeo JH; Andrade OC; Cromer D; Suarna C; Lam M; Maghzal GJ; Chong BH; Parish CR; Stocker R, 2015, 'Heme oxygenase-1 deficiency alters erythroblastic Island formation, steady-state erythropoiesis and red blood cell lifespan in mice', Haematologica, 100, pp. 601 - 610,
    Journal articles | 2015
    Khoury DS; Cromer D; Best SE; James KR; Sebina I; Haque A; Davenport MP, 2015, 'Reduced erythrocyte susceptibility and increased host clearance of young parasites slows Plasmodium growth in a murine model of severe malaria', Scientific Reports, 5, pp. 9412,
    Journal articles | 2015
    Martyushev AP; Petravic J; Grimm AJ; Alinejad-Rokny H; Gooneratne SL; Reece JC; Cromer D; Kent SJ; Davenport MP, 2015, 'Epitope-specific CD8+ T cell kinetics rather than viral variability determine the timing of immune escape in simian immunodeficiency virus infection', Journal of Immunology, 194, pp. 4112 - 4121,
    Journal articles | 2015
    Pinkevych M; Cromer D; Tolstrup M; Grimm AJ; Cooper DA; Lewin SR; Søgaard OS; Rasmussen TA; Kent SJ; Kelleher AD; Davenport MP, 2015, 'HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission', PLoS Pathogens, 11, pp. e1005000,
    Journal articles | 2015
    Tey SK; Davenport MP; Hill GR; Kennedy GA; Durrant ST; Khanna R; Cromer D, 2015, 'Post transplant CMV-specific T-cell immune reconstitution in the absence of global T-cell immunity is associated with a high risk of subsequent virus reactivation', Bone Marrow Transplantation, 50, pp. 315 - 316,
    Journal articles | 2015
    Waugh C; Cromer D; Grimm A; Chopra A; Mallal S; Davenport M; Mak J, 2015, 'A general method to eliminate laboratory induced recombinants during massive, parallel sequencing of cDNA library', Virology Journal, 12, pp. 55,
    Journal articles | 2014
    Schlub TE; Grimm AJ; Smyth RP; Cromer D; Chopra A; Mallal S; Venturi V; Waugh C; Mak J; Davenport MP, 2014, 'Fifteen to twenty percent of HIV substitution mutations are associated with recombination', Journal of Virology, 88, pp. 3837 - 3849,
    Journal articles | 2014
    Smyth RP; Schlub TE; Grimm AJ; Waugh C; Ellenberg P; Chopra A; Mallal S; Cromer D; Mak J; Davenport MP, 2014, 'Identifying Recombination Hot Spots in the HIV-1 Genome', Journal of Virology, 88, pp. 2891 - 2902,
    Journal articles | 2014
    Yabas M; Coupland LA; Cromer D; Winterberg M; Teoh NC; D'rozario J; Kirk K; Bröer S; Parish CR; Enders A, 2014, 'Mice deficient in the putative phospholipid flippase Atp11c exhibit altered erythrocyte shape, anemia, and reduced erythrocyte life span', Journal of Biological Chemistry, 289, pp. 19531 - 19537,
    Journal articles | 2013
    Cromer D; Best SE; Engwerda CR; Haque AKMM; Davenport MP, 2013, 'Where Have All the Parasites Gone? Modelling Early Malaria Parasite Sequestration Dynamics', PLoS ONE, 8, pp. Article number 55961,
    Journal articles | 2013
    Cromer D; Tey SK; Khanna R; Davenport MP, 2013, 'Estimating cytomegalovirus growth rates by using only a single point', Journal of Virology, 87, pp. 3376 - 3381,
    Journal articles | 2013
    Cromer D; van Hoek AJ; Jit M; Edmunds WJ; Fleming D; Miller E, 2013, 'The burden of influenza in England by age and clinical risk group: A statistical analysis to inform vaccine policy', Journal of Infection, 68, pp. 363 - 371,
    Journal articles | 2013
    Khoury DS; Cromer D; Best SE; James KR; Kim PS; Engwerda CR; Haque A; Davenport MP, 2013, 'Effect of mature, blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.', Infection and Immunity, 82, pp. 212 - 220,
    Journal articles | 2013
    Lucy C; Yabas M; Cromer D; Winterberg M; Teoh N; Kirk K; Broer S; Parish C; Enders A, 2013, 'Anemia, Shortened Erythrocyte Lifespan and Stomatocytosis In a Flippase Mutant Mouse Strain', Blood, 122, pp. 2183 - 2183,
    Journal articles | 2013
    Tey SK; Kennedy GA; Cromer D; Davenport MP; Walker S; Jones LI; Crough T; Durrant ST; Morton JA; Butler JP; Misra AK; Hill GR; Khanna R, 2013, 'Clinical Assessment of Anti-Viral CD8+ T Cell Immune Monitoring Using QuantiFERON-CMV® Assay to Identify High Risk Allogeneic Hematopoietic Stem Cell Transplant Patients with CMV Infection Complications', PLoS ONE, 8, pp. e74744,
    Journal articles | 2010
    Chan ML; Petravic J; Ortiz AM; Engram J; Paiardini M; Cromer D; Silvestri G; Davenport MP, 2010, 'Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys', Proceedings of the Royal Society of London Series B - Biological Sciences, 277, pp. 3773 - 3781
    Journal articles | 2010
    Coupland LA; Cromer D; Davenport MP; Parish CR, 2010, 'A novel fluorescent-based assay reveals that thrombopoietin signaling and Bcl-X(L) influence, respectively, platelet and erythrocyte lifespans', Experimental Hematology, 38, pp. 453 - 461
    Journal articles | 2010
    Cromer D; Wolinsky S; Mclean A, 2010, 'How fast could HIV change gene frequencies in the human population?', Proceedings of the Royal Society B - Biological Sciences, 277, pp. 1981 - 1989
    Journal articles | 2010
    Jit M; Cromer D; Baguelin M; Stowe J; Andrews N; Miller E, 2010, 'The cost-effectiveness of vaccinating pregnant women against seasonal influenza in England and Wales', Vaccine, 29, pp. 115 - 122
    Journal articles | 2009
    Cromer D; Christophides G; Stark J, 2009, 'Hidden variable analysis of transcription factor cooperativity from microarray time courses', IET Systems Biology, 4, pp. 131 - 144
    Journal articles | 2009
    Cromer D; Stark J; Davenport MP, 2009, 'Low red cell production may protect against severe anemia during a malaria infection--insights from modeling', Journal of Theoretical Biology, 257, pp. 533 - 542
    Journal articles | 2006
    Cromer D; Evans KJ; Schofield L; Davenport MP, 2006, 'Preferential invasion of reticulocytes during late-stage Plasmodium berghei infection accounts for reduced circulating reticulocyte levels', International Journal for Parasitology, 36, pp. 1389 - 1397
  • Working Papers | 2021
    Cele S; Jackson L; Khoury DS; Khan K; Moyo-Gwete T; Tegally H; San JE; Cromer D; Scheepers C; Amoako D; Karim F; Bernstein M; Lustig G; Archary D; Smith M; Ganga Y; Jule Z; Reedoy K; Hwa S-H; Giandhari J; Blackburn JM; Gosnell BI; Abdool Karim SS; Hanekom W; NGS-SA ; COMMIT-KZN Team ; von Gottberg A; Bhiman J; Lessells RJ; Moosa M-YS; Davenport MP; de Oliveira T; Moore PL; Sigal A, 2021, SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection., ,
  • Preprints | 2024
    Berry M; MacIntyre R; Cromer D; Hacker A; Davenport M; Khoury D, 2024, Optimal deployment of limited vaccine supplies to combat mpox,
    Preprints | 2024
    Conway E; Walker C; Lydeamore M; Golding N; Ryan G; Mavec D; Oates J; Kabashima G; Price DJ; Shearer F; Cromer D; Davenport MP; McCaw J; Eriksson EM; Hodgkin PD; Wu L; Le TP; Baker CM; Mueller I; McVernon J, 2024, Optimal timing of booster doses in a highly vaccinated population with minimal natural exposure to COVID-19,
    Preprints | 2024
    Cromer D; Reynaldi A; Hie A; Schlub T; Juno J; Wheatley A; Kent S; Khoury D; Davenport M, 2024, Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates,
    Preprints | 2024
    Hao T; Ryan GE; Lydeamore MJ; Cromer D; Wood J; McVernon J; McCaw JM; Shearer FM; Golding N, 2024, Predicting immune protection against outcomes of infectious disease from population-level effectiveness data with application to COVID-19,
    Preprints | 2023
    Elias K; Khan S; Stadler E; Schlub T; Cromer D; Polizzotto M; Kent S; Turner T; Davenport M; Khoury D, 2023, Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: A systematic review and meta-analysis,
    Preprints | 2023
    Le T; Conway E; Akpan E; Abell I; Abraham P; Baker C; Campbell P; Cromer D; Lydeamore M; McDonough Y; Mueller I; Ryan G; Walker C; Wang Y; Carvalho N; McVernon J, 2023, Cost-effective boosting allocations in the post-Omicron era of COVID-19 management,
    Preprints | 2023
    Lee WS; Tan H-X; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent H; Aggarwal A; Turville S; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson D; Cromer D; Davenport M; Kent S; Juno J; Khoury D; Wheatley A, 2023, Durable reprogramming of neutralising antibody responses following breakthrough Omicron infection,
    Preprints | 2023
    Selva KJ; Ramanathan P; Haycroft ER; Reynaldi A; Cromer D; Tan CW; Wang L-F; Wines B; Hogarth M; Downie L; Davis S; Purcell RA; Kent H; Juno J; Wheatley A; Davenport M; Kent SJ; Chung A, 2023, Lasting first impression: Pre-existing immunity restricts mucosal antibody responses during Omicron breakthrough,
    Preprints | 2022
    Cromer D; Steain M; Reynaldi A; Schlub T; Sasson S; Kent S; Khoury D; Davenport MP, 2022, Neutralising antibodies predict protection from severe COVID-19,
    Conference Posters | 2022
    Docken S; McCormick K; Pampena M; Pinkevych M; Viox E; Keele B; Paiardini M; Betts M; Bar K; Davenport M; Samer S; Cromer D; Schlub T, 2022, 'PP 2.3 – 00034 CD8+ T-Cell Sieving During SIV Reactivation from Latency', Vol. 8, pp. 100159 - 100159,
    Preprints | 2022
    Khoury D; Docken S; Subbarao K; Kent S; Davenport M; Cromer D, 2022, Predicting the efficacy of variant-modified COVID-19 vaccine boosters,
    Preprints | 2022
    Khoury D; Schlub T; Cromer D; Steain M; Fong Y; Gilbert P; Subbarao K; Triccas J; Kent S; Davenport M, 2022, Correlates of protection, thresholds of protection, and immunobridging in SARS-CoV-2 infection,
    Conference Papers | 2022
    Lau JSY; Cromer D; Pinkevych M; Lewin SR; Rasmussen TA; McMahon JH; Davenport MP, 2022, 'Balancing Statistical Power and Risk in HIV Cure Clinical Trial Design', in Journal of Infectious Diseases, pp. 236 - 245,
    Preprints | 2022
    Stadler E; Burgess M; Schlub T; Chai KL; McQuilten Z; Wood E; Polizzotto M; Kent S; Cromer D; Davenport M; Khoury D, 2022, Monoclonal antibody levels and protection from COVID-19,
    Preprints | 2022
    Stadler E; Chai KL; Schlub T; Cromer D; Polizzotto M; Kent S; Beecher C; White H; White H; Turner T; Skoetz N; Skoetz N; Estcourt L; McQuilten Z; Wood E; Khoury D; Davenport M, 2022, Determinants of passive antibody efficacy in SARS-CoV-2 infection,
    Preprints | 2022
    Stadler E; Cromer D; Mehra S; Adekunle A; Flegg J; Anstey N; Watson J; Chu C; Mueller I; Robinson L; Schlub T; Davenport M; Khoury D, 2022, Risk of Plasmodium vivax recurrences follows a 30-70 rule and indicates relapse heterogeneity in the population,
    Preprints | 2022
    Stadler E; Cromer D; Ogunlade S; Ongoiba A; Doumbo S; Kayentao K; Traore B; Crompton P; Portugal S; Davenport M; Khoury D, 2022, A role for super-spreaders in carrying malaria parasites across the months-long dry season,
    Preprints | 2021
    Aggarwal A; Stella AO; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Henry J; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fichter C; Hoppe AC; Munier ML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2021, SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern,
    Preprints | 2021
    Khoury D; Steain M; Triccas J; Sigal A; Davenport M; Cromer D, 2021, A meta-analysis of Early Results to predict Vaccine efficacy against Omicron,
    Preprints | 2021
    Koutsakos M; Lee WS; Reynaldi A; Tan H-X; Gare G; Kinsella P; Liew KC; Williamson D; Kent H; Stadler E; Cromer D; Khoury D; Wheatley A; Juno J; Davenport M; Kent S, 2021, Dynamics of immune recall following SARS-CoV-2 vaccination or breakthrough infection,
    Conference Abstracts | 2021
    Lansink LIM; Engel JA; Lee HJ; Soon MSF; Williams CG; Aogo RA; Cromer D; Davenport MP; Khoury DS; Haque A, 2021, 'Exposure to host inflammation in vivo induces rapid transcriptomic change and impaired maturation in malaria parasites', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Vol. 206,
    Preprints | 2020
    Lee WS; Selva KJ; Davis S; Wines B; Reynaldi A; Esterbauer R; Kelly H; Haycroft E; Tan H-X; Juno J; Wheatley A; Hogarth M; Cromer D; Davenport M; Chung A; Kent S, 2020, Decay of Fc-dependent antibody functions after mild to moderate COVID-19,
    Preprints | 2020
    Price D; Shearer F; Meehan M; McBryde E; Moss R; Golding N; Conway E; Dawson P; Cromer D; Wood J; Abbott S; McVernon J; McCaw J, 2020, Early analysis of the Australian COVID-19 epidemic,
    Preprints | 2020
    Wheatley A; Juno J; Wang J; Selva K; Reynaldi A; Tan H-X; Shi Lee W; Wragg K; Kelly H; Esterbauer R; Davis S; Kent H; Mordant F; Schlub T; Gordon D; Khoury D; Subbarao K; Cromer D; Gordon T; Chung A; Davenport M; Kent S, 2020, Evolution of immunity to SARS-CoV-2,
    Preprints | 2017